Modulation of Immune Response Using Engineered Nanoparticle Surfaces
نویسندگان
چکیده
منابع مشابه
Nanoparticle hydrophobicity dictates immune response.
Understanding the interactions of nanomaterials with the immune system is essential for the engineering of new macromolecular systems for in vivo applications. Systematic study of immune activation is challenging due to the complex structure of most macromolecular probes. We present here the use of engineered gold nanoparticles to determine the sole effect of hydrophobicity on the immune respon...
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1 Departamento de Cĺınica Medica, Laboratório de Imunofarmacologia Experimental (LIFE), Instituto de Ciências da Saúde, Universidade Federal do Triângulo Mineiro (UFTM), Rua Vigário Carlos 162, 38025-350 Uberaba, MG, Brazil 2 Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil 3 Universidade Federal de Santa Catarina (UFSC), Florian...
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Characterisation of engineered nanomaterials (NMs) is of outmost importance for the assessment of the potential risks arising from their extensive use. NMs display indeed a large variety of physico-chemical properties that drastically affect their interaction with biological systems. Among them, hydrophobicity is an important property that is nevertheless only slightly covered by the current ph...
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ژورنال
عنوان ژورنال: Small
سال: 2015
ISSN: 1613-6810
DOI: 10.1002/smll.201502273